hrp0097p1-323 | Growth and Syndromes | ESPE2023

A systematic review of core outcomes reported in clinical trials of growth hormone therapy in children with growth hormone deficiency

Tseretopoulou Xanthippi , Lucas-Herald Angela , Chen Jiajia , Bachega Tania , Charmandari Evangelia , Choi Jin-Ho , Dou Xinyu , Gong Chunxiu , Hamza Rasha , Harvey Jamie , R. Hoffman Andrew , Horikawa Reiko , Johannsson Gudmundur , Jorge Alexander , S. Miller Bradley , Roehrich Sebastian , Sävendahl Lars , Vitali Diana , Wajnrajch Michael , Ching Chen Suet , Faisal Ahmed Syed

Introduction: Although the safety and effectiveness of recombinant human growth hormone therapy (rhGH) has been reported for several years, the level of consensus on the outcomes that should be reported is unclear. The aim of this systematic review is to study the frequency of reporting of these outcomes in children with GH deficiency (GHD).Methods: A systematic review was performed in Medline, Embase, Cochrane Central R...